Invited Speakers

Cells as factories and therapies: modernizing biologics production for emerging modalities

Andreas Pluckthun (University of Zurich) - Precision gene delivery through protein engineering
Isabelle Riviere (Takeda, USA) - Evolving CAR cell Therapies
Zoltan Ivics (Paul Ehrlich Institute, Frankfurt) - The Sleeping Beauty transposon system: A molecular parasite tamed for genome engineering

Product Quality – Functional Relevance and Emerging Technologies

Jamie Piret (UBC, Canada) - Process Analytical Utility of Raman Microscopy for Cell Therapy Manufacturing
Jonathan Bones (NIBRT, Ireland) - Making analytical characterisation routine
Rena Mizrahi (Gigagen, USA) - Control and Characterization of Thousands-Diverse Recombinant Polyclonal Antibodies

From Big Data to Better Cells and Processes

Moritz von Stosch (DataHow, Switzerland) - Towards digital process development - How (hybrid) modeling and transfer learning could change the way we develop and operate processes
Zan Luthney-Schulten (University of Illinois, USA) - 4D simulations of a growing minimal bacterial cell

Transitioning from development to manufacture - How do science and innovation translate into highly efficient biomanufacturing?

Brian Shy (University of California, USA) - Developing and manufacturing CRISPR-engineered T cell therapies in the academic setting
Cath Green (University of Oxford, UK) - Scaling-up Covid vaccine manufacture: Combating the pandemic
Jyothsna Viswesvaraiah (Seismic, USA) - Mitigating risk during biologics manufacturing using discovery stage developability assays and state of the art machine learning based optimization

ESACT 2024 BEGINS

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